Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
J Pers Med. 2023 Oct 31;13(11):1566. doi: 10.3390/jpm13111566. ABSTRACT Tadalafil and finasteride are used in combination for the management of benign prostatic hyperplasia (BPH). Genetic variations in genes involved in the metabolism and transport of tadalafil or finasteride (i.e., pharmacogenes) could affect their pharmacokinetic processes altering their drug exposure, efficacy, and toxicity. The main objective…