EJHaem. 2023 Sep 27;4(4):1052-1058. doi: 10.1002/jha2.799. eCollection 2023 Nov. ABSTRACT Methotrexate is an essential drug in the treatment of childhood cancer that is not exempt from toxicities. Glucarpidase is a drug used to reduce the toxic concentration of plasma methotrexate in patients with delayed elimination or at risk of toxicity. We describe the characteristics of…
J Pers Med. 2023 Oct 31;13(11):1566. doi: 10.3390/jpm13111566. ABSTRACT Tadalafil and finasteride are used in combination for the management of benign prostatic hyperplasia (BPH). Genetic variations in genes involved in the metabolism and transport of tadalafil or finasteride (i.e., pharmacogenes) could affect their pharmacokinetic processes altering their drug exposure, efficacy, and toxicity. The main objective…
La reciente aprobación de la actualización de la cartera de servicios comunes de atención especializada en el marco del Sistema Nacional de Salud (SNS) ha dado lugar a la integración de análisis genéticos predictivos como una herramienta fundamental. Estos análisis son aplicados de manera específica en individuos que requieren la administración de ciertos medicamentos contemplados…
Clin Pharmacol Ther. 2023 Nov 16. doi: 10.1002/cpt.3093. Online ahead of print. NO ABSTRACT PMID:37970726 | DOI:10.1002/cpt.3093
