CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride
Clin Transl Sci. 2022 Nov;15(11):2613-2624. doi: 10.1111/cts.13386. Epub 2022 Sep 6. ABSTRACT Cinitapride is a gastrointestinal prokinetic drug, prescribed for the treatment of functional dyspepsia, and as an adjuvant therapy for gastroesophageal reflux disease. In this study, we aimed to explore the impact of relevant variants in CYP3A4 and CYP2C8 and other pharmacogenes, along with…
