Bioavailability of Oniria®, a Melatonin Prolonged-Release Formulation, Versus Immediate-Release Melatonin in Healthy Volunteers

Drugs R D. 2022 Sep;22(3):235-243. doi: 10.1007/s40268-022-00394-3. Epub 2022 Aug 2. ABSTRACT BACKGROUND: Melatonin is an endogenous substance which plays a key role in sleep induction by reducing sleep onset latency; it has been approved by the European Food Safety Authority as a food supplement for exogenous administration. Oniria® is a food supplement formulated as…