Pharmacogenetics of Donepezil and Memantine in Healthy Subjects

J Pers Med. 2022 May 13;12(5):788. doi: 10.3390/jpm12050788. ABSTRACT Donepezil and memantine are the most common drugs used for Alzheimer’s disease. Their low effectiveness could partly be explained by genetic factors. Thus, we aim to identify Single Nucleotide Polymorphisms (SNPs) associated with pharmacokinetics, pharmacodynamics, and the safety of donepezil and memantine. For this regard, 25…